NM_000443.4(ABCB4):c.504C>T (p.Asn168=) AND Progressive

asn168Glycosylation site Asn168 is important for slow in vivo clearance of recombinant human diamine oxidase heparinIntact N-glycans at Asn168 seem to protect DAO from rapid clearance in rodents. Full processing of all glycoforms is critical for preserving the improved in vivo half-life